This depends a lot on each individual, destination and time of the year, but these are some items that are often very useful in Africa: spare batteries for photographic equipment, international plug adaptors, binoculars, windbreak, sunglasses, sunscreen, insect repellent, general medicines, toiletries, education, common sense and good humor. Most of these items can be easily purchased in South Africa, but not in other countries. Preventive and regular medicines should always be taken from your country of origin.